Network meta-analysis: introduction and an example that compares devices for PFO closure

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Network meta-analysis: introduction and an example that compares devices for PFO closure.

Over the last 20 years, the number of published meta-analyses has exploded and, therefore, clinicians have become more familiar with this study design. The results of different trials are statistically combined to produce a more precise estimate [i.e. an estimate with a narrower confidence interval (CI)]. When a meta-analysis is performed after a credible systematic review, the results become m...

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T he optimal secondary prevention strategy in patients presenting with a cryptogenic stroke or transient ischemic attack (TIA) and a patent foramen ovale (PFO) is uncertain. In the United States, closure of a PFO using a percutaneous transcatheter device is currently considered investigational by the Food and Drug Administration. Nonetheless, many patients in this setting are treated off-label ...

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Multivariate Network Meta-Analysis: An Example In Type 2 Diabetes For The Analysis Of Glycaemic Control.

Methods • Network meta-analyses are commonly conducted within a Bayesian framework to enable the ranking of interventions, based on the probability of each treatment to be associated with the best efficacy. • Multivariate models have been developed to deal with correlation between outcomes as they allow to account for the within-study correlation between endpoints. • Moreover, the multivariate ...

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cohesion and cohesive devices in a contrastive analysis between ge and esp texts

the present study was an attempt to conduct a contrastive analysis between general english (ge) and english for specific purposes (esp) texts in terms of cohesion and cohesive devices. to this end, thirty texts from different esp and ge textbooks were randomly selected. then they were analyzed manually to find the frequency of cohesive devices. cohesive devices include reference, substitution, ...

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Network Meta-analysis of Randomized Trials on the Safety of Vascular Closure Devices for Femoral Arterial Puncture Site Haemostasis

BACKGROUND Vascular closure devices (VCDs) are widely used to achieve haemostasis after procedures requiring percutaneous common femoral artery (CFA) puncture. There is no consensus regarding the benefits of VCDs, including potential reduction in procedure time, length of hospital stay or time to patient ambulation. No robust evidence exists that VCDs reduce the incidence of puncture site compl...

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ژورنال

عنوان ژورنال: European Heart Journal

سال: 2014

ISSN: 1522-9645,0195-668X

DOI: 10.1093/eurheartj/ehu343